Autism spectrum disorder (ASD) is a developmental condition that affects a person’s ability to socialize and communicate with others. People with ASD can also present with restricted and/or repetitive patterns of behavior, interests or activities. The term “spectrum” refers to the degree in which the symptoms, behaviors and severity vary within and between individuals. Some people are mildly impaired by their symptoms, while others are severely disabled.

Based on Centers for Disease Control and Prevention (CDC) suveillance, an average of 1 in every 59 8-year-old children in the U.S. have ASD. Boys are four times more likely than girls to develop symptoms of ASD. Children across across demographic and socioeconomic groups experience ASD. Awareness  and improved screening methods have contributed to the increase in diagnoses in recent years.

Symptoms

For most, symptoms of ASD often start to appear during the first three years of life (though a small percentage of people might not receive a diagnosis until later in life). Typically, developing infants are social by nature. They gaze at faces, turn toward voices, grasp a finger and even smile by 2-3 months of age. Most children who develop autism have difficulty engaging in everyday human interactions.

Not everyone will experience symptoms with the same severity, but most people with ASD will have symptoms that affect social interactions and relationships. ASD can also causes difficulties with verbal and nonverbal communication and preoccupation with certain activities. Along with different interests, children with ASD generally have different ways of interacting with others. Parents are often the first to notice that their child is showing unusual behaviors. These behaviors can include failing to make eye contact, not responding to his or her name or playing with toys in unusual, repetitive ways.

Symptoms of autism can include impairments to social interaction & communication, and restricted and repetitive patterns of behavior. More specific symptoms are outlined below:

• Delay in language development, such as not responding to their own name or speaking only in single words, if at all.
• Repetitive and routine behaviors, such as walking in a specific pattern or insisting on eating the same meal every day.
• Difficulty making eye contact, such as focusing on a person’s mouth when that person is speaking instead of their eyes, as is usual in most young children.
• Sensory dysregulation forms a strong component of ASD. This often presents as hyper (overly-sensitive) or hyposensitivity (less sensitive) to certain sensory stimuli. Examples include experiencing pain or pleasure from certain sounds, like a ringing telephone or not reacting to intense cold or pain, certain sights, sounds, smells, textures and tastes. The physical and emotional response in these cases can be very overwhelming and result in sensory overload, often leading to meltdowns.
• Difficulty interpreting subtle gestures & facial expressions, such as misreading or not noticing subtle facial cues, like a smile, wink or grimace, that could help understand the nuances of social communication.
• Problems in expressing emotions, such as facial expressions, movements, tone of voice and gestures that are often vague or do not match what is said or felt.
• Fixation on parts of objects, often to the detriment of understanding the “whole” such as focusing on a rotating wheel instead of playing with peers.
• Absence of pretend play, such as taking a long time to line up toys in a certain way, rather than playing with them.
• A lack of social understanding that makes interaction with peers challenging
• Self-injurious behavior. Individuals with ASD will often appear to hurt themselves in response to certain activities or environments.
• Sleep problems, such as falling asleep or staying asleep.

The learning, thinking and problem-solving abilities of people with ASD can range from gifted to severely challenged. Some people with ASD need a lot of help in their daily lives. With a thorough evaluation, doctors can make a diagnosis to help find the best treatment plan.

Causes

Scientists have not discovered a single cause of autism. They believe several factors may contribute to this developmental disorder.

• Genetics. If one child in a family has ASD, another sibling is more likely to develop it too. Likewise, identical twins are highly likely to both develop autism if it is present. Relatives of children with autism show minor signs of communication difficulties. Scans reveal that people on the autism spectrum have certain abnormalities of the brain’s structure and chemical function.
• Environment. Scientists are currently researching many environmental factors that are thought to play a role in contributing to ASD. Many prenatal factors may contribute to a child’s development, such as a mother’s health. Other postnatal factors may affect development as well. Despite many claims that have been highlighted by the media, strong evidence has been shown that vaccines do not cause autism.

Diagnosis

There is no medical test that can determine the possibility of developing autism. Specialists make the diagnosis after screening for social and communication difficulties, and repetitive or restricted behaviors.

Diagnosing autism is often a 2-stage process. The first stage involves general developmental screening during well-child checkups with a pediatrician. Children who show some developmental problems are referred for more evaluation. The second stage involves a thorough evaluation by a team of doctors and other health professionals with a wide range of specialties. At this stage, a child may be diagnosed as having autism or another developmental disorder. Typically, children with ASD can be reliably diagnosed by age two, though some may not be diagnosed until they are older.

Types Of ASD Screening Instruments
Sometimes the doctor will ask parents questions about the child’s symptoms to screen for autism. Other screening instruments combine information from parents with the doctor’s own observations of the child. Examples of screening instruments for toddlers and preschoolers include:

• Modified Checklist for Autism in Toddlers (M-CHAT) is a list of informative questions about a child where the answers can show whether he or she should be further evaluated by a specialist.
• Screening Tool for Autism in Two-Year-Old’s (STAT) is a set of tasks that children perform under supervision to assess key social and communicative behaviors, including imitation, play and directing attention.
• Social Communication Questionnaire (SCQ) is a series of questions parents answer to help specialists determine if further testing is needed for a child aged 4 years or older.
• Communication and Symbolic Behavior Scales (CSBS) uses parent interviews and direct observations of natural play to collect information on communication development, including gestures, facial expressions and play behaviors.

For more information on these screening tools, please visit the Centers for Disease Control and Prevention.

Treatment

Given that ASD is a developmental condition that begins early in life, having a cascading effect on developmental milestones, there is no known cure. But there is effective treatment available. Treatment options include:

• Education and development, including specialized classes and skills training, time with therapists (such as Speech & Language and Occupational Therapists) and other specialists
• Behavioral treatments, such as applied behavior analysis (ABA)
• Medication for co-occurring symptoms, combined with therapy
• Complementary and alternative medicine (CAM), such as supplements and changes in diet

Related Conditions

A child with autism may have co-morbid disorders. Some of those disorders are:

• Intellectual impairment. Many children with ASD have some degree of intellectual impairment. Cognitive and language skills may be weak in a number of domains, often having a profound impact on daily functioning.
• Seizures. 1 in 4 children with autism has seizures, often starting either in early childhood or during the teen years. Seizures, caused by electrical activity in the brain, can result in a short-term loss of consciousness, convulsions and staring spells. An electroencephalogram (EEG), a nonsurgical test that records electrical activity in the brain, can help confirm whether a child is having seizures.
• Fragile X syndrome. Fragile X syndrome is a genetic disorder. It is the most common form of inherited intellectual impairment, and often results in ASD-like symptoms. Around 1 in 3 children who have Fragile X syndrome also meet the diagnostic criteria for ASD. About 1 in 25 children diagnosed with ASD have the gene mutation that causes Fragile X syndrome. Because this disorder is inherited, children with autism should be checked for Fragile X, especially if the parents want to have more children. For more information on Fragile X, see the Eunice Kennedy Shriver National Institute of Child Health and Human Development website.
• Tuberous sclerosis. Tuberous sclerosis is a rare genetic disorder that causes noncancerous tumors to grow in the brain and other vital organs. Tuberous sclerosis occurs in 1-4% of people with ASC. A genetic mutation causes the disorder, which has also been linked to intellectual impairment, epilepsy and many other physical and mental health problems. There is no cure for tuberous sclerosis, but many symptoms can be treated.
• Gastrointestinal problems. Some parents of children with autism report that their child has frequent gastrointestinal (GI) or digestion problems including stomach pain, diarrhea, constipation, acid reflux, vomiting or bloating. If a child has GI problems, a gastroenterologist can help find the cause and suggest appropriate treatment.
• Mental health conditions. Children with autism can also develop mental health conditions such as Anxiety Disorders, Attention Deficit Hyperactivity Disorder (ADHD) or Depression. Research shows that children with ASC are at higher risk for some mental health conditions than children without autism. Managing these co-occurring conditions with medications or behavioral therapy, which teaches children how to control their behavior, can reduce symptoms that appear to worsen a child’s symptoms.
• Rett syndrome. Rett syndrome is a developmental disorder that includes a regression in development. Unlike ASD, Rett syndrome mostly affects girls. 1 of every 10,000-22,000 girls has Rett syndrome. Children with Rett syndrome develop normally for 6-18 months before regression and ASD-like symptoms appear. However, after this period, most children with Rett syndrome improve their social communication skills, and autistic features are no longer a major area of concern.

Treatment plans for autism spectrum disorder (ASD) are tailored to each person’s unique needs. These can consist of medications, therapy or both. Many therapists work closely with autistic individuals using a variety of therapies to help increase social and communication skills.

Psychotherapy

Educational and behavioral approaches are often a main feature of the overall treatment plan for children. Most health care professionals will implement an early intensive behavioral intervention, involving the child’s entire family in education and training. In some early intervention programs, therapists come into the home to deliver services. Other programs deliver therapy in a specialized center, classroom or preschool. Types of therapy may include:

Applied Behavioral Analysis (ABA). ABA is one of the most researched behavioral therapies for autism. It teaches children positive behavior while discouraging the negative. A child, for example, may be directed to hand his therapist a pencil. If he does, he will receive a reward, such as praise or a small toy. If he doesn’t, he will receive a prompt, such as the therapist moving his hand to the pencil.

Floor time. This therapy targets speech, motor or cognitive skills through its focus on emotional development through interactive play between parents and children. Overall, it aims to help children learn a number of developmental skills, including interpersonal interaction, emotional thinking and advanced communication.

Education and development. Most children with autism respond well to highly structured, specialized treatment, especially in a school setting. Teachers and parents should discuss how to develop a plan that works best for the child’s needs. Suggestions may include:

• Smaller classes with individual time with teachers and therapists
• Focusing on tasks that may be difficult for a few hours a day
• Learning skills for adapting to new situations
• Having structure and a schedule to reduce distractions

Medications

There are no FDA-approved medications for the core symptoms of ASD. Two antipsychotic medicines, Aripipazole and Resperiodone, have been approved for irritability associated with autism. Other off-label medications are best used in combination with psychotherapy and other interventions. They should target specific symptoms with an outcome to measure their effectiveness. Please consult a psychiatrist on the best medication plan for the individual.

Complementary And Alternative Approaches

CAM, known as integrative medicine, looks at other factors that can have a positive influence on the symptoms of ASD.

• Melatonin is a natural sleep supplement. Many people with autism have sleep disorders, and melatonin helps regulate sleep cycles. Sleep patterns are important to regulate to help with other symptoms like repetitive behavior.
• Nutritional Supplements, like multivitamins, can help replenish nutrients, especially when a person has an unbalanced diet. They can be good for overall health
• Gluten and Casein-Free Diet has led some families to report that taking certain foods out of their children’s diet has helped with their behavior. Foods with wheat or dairy may irritate the GI tract, which in turn increases ASD symptoms.

Managing the symptoms of autism can be difficult. If you or your child is struggling, there is help. NAMI and NAMI affiliates are there to provide you with support for you and your family and information about community resources.

Contact the NAMI Helpline at 1-800-950-6264 or [email protected] if you have any questions about autism spectrum disorder (ASD) or finding support and resources.

Helping Yourself

ASD often poses a challenge to a person’s ability to interact in society. Lack of education and stigma leaves many people unable to understand that this is a medical disorder. Even for adults, the negative associations others make are more damaging than the symptoms themselves. Fortunately, there are options:

• Connect with others. The Interactive Autism Network has an entire section dedicated to helping adults on the ASD spectrum find support and information on subjects ranging from housing services to romantic relationships.
• Educate yourself.  If you live with a mental health condition, learn more about managing your mental health and finding the support you need.

Helping A Family Member Or Friend

• Share your experiences. It can be very frustrating for both people with ASD and family members because of the challenges of communicating. Support groups can help families better understand each other’s needs. Talk About Curing Autism (TACA) and Autism Help are two great places to start.
• Use resources. The Social Security Administration can direct families to government-funded programs to help children with ASD. The U.S. Department of Health and Human Services, and the Centers for Disease Control and Prevention have extensive information on programs and organizations to help.

Find out more about taking care of your family member or friend and yourself.